Aim:
To compare and evaluate the early and late results of open and laparoscopic retropubic prostatectomy in the surgical treatment of large benign prostatic hyperplasia (more than 80 ml).

Material and methods:
Early and late results of one-stage laparoscopic extraperitoneal retropubic prostatectomy in 50 patients with benign prostatic hyperplasia and 120 one-stage open retropubic prostatectomies in the period from 2021 to 2023.

Results:
The average time of laparoscopic prostatectomy - 120.3 ÷ 11.7 minutes, open - 81.1 ≤ 17.4; average intraoperative blood loss - 118.7 ÷ 33.6 ml and 520.5 ÷ 67.4 ml, postoperative bed-day 6.1 ÷ 1.1 and 9.8 $ 2.9, respectively. Transfusion of blood components - in 9 (7.5%) patients after open retropubic prostatectomy, never after laparoscopic. Urological complications after laparoscopic prostatectomy - in 2% of patients, open - 19.2%, complications according to Clavien - Dindo - 4% and 33.3%, respectively. Laparoscopic and open retropubic nrostatectomies allow eduall effective restoration of the art of urination after surgerv late results of treatment and postoperative complications were less (2.5% versus 8%) after laparoscopic retropubic prostatectomy.

Conclusions:
Laparoscopic and open retropubic prostatectomy are effective operations for the treatment of patients with benign prostatic hyperplasia of large size (more than 80 ml) with satisfactory early and late results, as well as restoration of urination. In the hands of an experienced laparoscopic surgeon, laparoscopic retropubic prostatectomy can achieve better treatment results, than open retropubic prostatectomy. This makes it possible to recommend laparoscopic retropubic prostatectomy in the practice of urologists of urological clinics of Ukraine where laparoscopic equipment are present.