Impact of lifestyle modification interventions on metabolic
syndrome and obesity in adults
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1
I. YA. HORBACHEVSKY TERNOPIL NATIONAL MEDICAL UNIVERSITY, TERNOPIL, UKRAINE
2
ODESA NATIONAL MEDICAL UNIVERSITY, ODESA, UKRAINE
3
SUMY STATE UNIVERSITY, SUMY, UKRAINE
Publication date: 2025-09-30
Wiadomości Lekarskie 2025;(9):1857-1865
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ABSTRACT
Aim: The aim of this review article is to provide a comprehensive analysis of the impact of lifestyle interventions – dietary modifications, physical activity, and
behavioral strategies – on the management of metabolic syndrome and obesity in adults.
Materials and Methods: This review is based on an analysis of recent studies, systematic reviews, and meta-analyses that investigate the relationship
between lifestyle modifications and improvements in MetS and obesity. Sources include peer-reviewed research articles, clinical trials, and public health data
on dietary interventions, physical activity, and behavioral strategies. The effectiveness of interventions was assessed through key metabolic parameters such
as weight loss, waist circumference reduction, insulin sensitivity, lipid profiles, and cardiovascular health markers.
Conclusions: Lifestyle interventions play a crucial role in managing MetS and obesity by addressing the underlying metabolic dysfunctions and reducing
the risk of related diseases, including cardiovascular disease and type 2 diabetes. However, long-term adherence remains a significant challenge. Emerging
approaches, such as technology-assisted self-monitoring and group-based programs, offer promising strategies to enhance engagement and effectiveness
Future efforts should focus on scalable, inclusive, and sustainable interventions to reduce the global burden of MetS and obesity.