Impact of hormonal disorders after surgical treatment of endocrine pathology on dermatologic status and the need for aesthetic rehabilitation
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1
STATE INSTITUTION OF SCIENCE «CENTER OF INNOVATIVE HEALTHCARE TECHNOLOGIES» STATE ADMINISTRATIVE DEPARTMENT, KYIV, UKRAINE
2
BOGOMOLETS NATIONAL MEDICAL UNIVERSITY, KYIV, UKRAINE
3
KYIV CITY CLINICAL HOSPITAL № 1, KYIV, UKRAINE
Publication date: 2026-06-30
Wiadomości Lekarskie 2026;(6):1231-1237
KEYWORDS
ABSTRACT
Aim:
To evaluate the impact of postoperative hormonal disorders on dermatologic status and to determine the need for aesthetic rehabilitation in patients
after surgical treatment of endocrine pathology.
Material and Methods:
A prospective cohort study included 128 patients aged 19–76 years after endocrine surgery. The sample comprised 54 patients after
thyroidectomy, 61 after parathyroidectomy, 3 after adrenalectomy, and 10 after combined procedures. Dermatologic examination, scar assessment, hormonal
profiling, and quality-of-life evaluation using SF-36 and DLQI were performed. Quantitative variables were summarized as mean ± standard deviation or median
and interquartile range; qualitative variables as absolute and relative frequencies. Comparative analysis used the chi-square test, relative risk (RR) with 95%
confidence interval (CI), and Pearson correlation (r).
Results:
Hormonal dysfunction was identified in 93 patients (72.7%). Dermatologic changes were found in 101 patients (78.9%), most commonly xerosis
(50.0%), pathological scarring (40.6%), alopecia (28.9%), and pigmentation disorders (24.2%). Patients with hormonal imbalance had a significantly higher
risk of dermatologic complications than those without endocrine dysfunction (88.2% vs 55.6%; RR = 1.59; 95% CI 1.21–2.08; p < 0.01). Aesthetic defects
requiring correction were identified in 76 patients (59.4%). Scar severity correlated with impaired dermatology-specific quality of life (r = 0.61; p < 0.001).
Conclusions:
Hormonal disorders after endocrine surgery are significantly associated with dermatologic complications and reduced quality of life. Integration
of dermatologic surveillance and aesthetic rehabilitation into postoperative care is clinically justified.