Aim: To enhance the effectiveness and safety of sun protection product use by developing recommendations based on an analysis of the Ukrainian SPF product market. Materials and Methods: A literature review was conducted using publications indexed in the databases Google Scholar, Web of Science, and Scopus, and the PubMed and ToxNet search engines. A structured search was conducted using relevant keywords and their logical combinations, including: “skin cancer” and “ultraviolet radiation”, “sunscreens”, “SPF products”, “sunscreen cosmetics”, “efficacy and safety of sunscreens”, and others. Information about sunscreens contained only on the official websites of the manufacturers was used. Information from unofficial sources was not considered. The review is based mainly on recent studies; however, selected scientific sources (2011-2018) were intentionally included to highlight the evolution of scientific knowledge in this field. The analysis used formal-logical and systemic-complex methods, which ensured a comprehensive and critical synthesis of the available evidence. Conclusions: Ultraviolet radiation is the main factor in the development of melanoma, basal cell carcinoma, and squamous cell carcinoma of the skin. The increasing incidence of skin cancer prompts health professionals to encourage the population to use sunscreens. Sun protection factor (SPF) serves as the main criterion for choosing the necessary level of protection in conditions of insolation. International recommendations support the use of preparations with high SPF indices, but in practice, frequent cases of inaccurate information provided by cosmetic manufacturers have been recorded. At the same time, cosmetic sunscreens, even with the same SPF value, demonstrate different levels of effectiveness under insolation conditions. The Ukrainian cosmetic market offers hundreds of SPF products in the form of creams, sprays, oils, milks, or foams. In addition to well-known brands from France, the USA, Italy, Switzerland, Germany, Poland, and Ukraine, dozens of brands from lesser-known manufacturers, especially from Korea, are now available thanks to online shopping. As a rule, such resources do not indicate the exact SPF used in the product but instead declare marketing characteristics such as “lightest” or “safest.” Today, their use is gaining popularity among the population; however, the need for legislative control over them must be addressed.