Aim: To provide a comprehensive overview of the biosuggestive therapy (BST), with a critical evaluation of its effectiveness in managing patients with stress-re lated and psychosomatic disorders, and to review the published research on its therapeutic applications across various clinical conditions. Materials and Methods: We conducted a literature search in the PubMed, Scopus, and Google Scholar databases for articles published between the early 2000s and mid-2025 that focus on examining the effectiveness of the BST method in managing and alleviating symptoms of various stress-related and psychosomatic disorders. During the literature search, we used the following set of key words: biosuggestive therapy, stress-related disorders, psychosomatic disorders, brain–gut axis, psychological distress, functional gastrointestinal disorders, and somatoform disorders. Considering the lack of research conducted and published to date, the authors compiled all the available information into a collection. We analyzed that collection, which ultimately contained 29 publications relevant to the topic of our review, and forwarded it for further analysis. Conclusions: BST is a safe and effective method for treating a wide range of stress-related and psychosomatic disorders. As a technique derived from hyp notherapy, its application in assisting individuals exposed to war-related trauma is gaining increasing attention. In addition, BST has demonstrated positive outcomes in the treatment of chronic pain, depression, anxiety, internet addiction, post-traumatic stress disorder, and logoneurosis. The presented evidence underscores the need for further research and broader implementation of this therapeutic approach.