Vertebral metastasis of hepatocellular carcinoma secondary to viral hepatitis b: case report of two patients
More details
Hide details
Rheumatology, Bogodogo University Hospital, Burkina Faso
Submission date: 2023-12-28
Acceptance date: 2024-01-24
Publication date: 2024-03-30
Corresponding author
Yannick Laurent Tchenadoyo BAYALA   

Rheumatology, Bogodogo University Hospital, Burkina Faso
Wiadomości Lekarskie 2024;77(2):358-362

Material and methods:

Case report:
Background: Bone metastases from liver cancer are rare. We report two cases of bone metastases revealing HCC. Case presentation: A 26-year-old african man presented with 4 months of low back pain in the context of general deterioration. Examination revealed a lumbar spinal syndrome and hepatomegaly. Abdominal ultrasound revealed a multinodular liver, and a CT scan of the spine revealed osteolytic lesions. Biological tests revealed a hepatic cytolysis syndrome, hepatic cholestasis and hepatocellular insufficiency. Alpha foetoprotein levels were elevated and hepatitis B serology was positive. We adopted the diagnosis of HCC of viral B origin with bone metastasis. The second case involved a 44-year-old African man admitted for 10 days with back pain. Examination revealed a spinal syndrome, paraplegia and hepatomegaly. A thoracic-abdominal-pelvic CT scan revealed typical HCC lesions and osteolytic lesions on the ribs, pelvis and vertebrae. The biology revealed a biological inflammatory syndrome, hepatic cytolysis, a hepatocellular insufficiency syndrome and a cholestasis syndrome. Alfa-feto proteins were elevated and HBV serology was positive. The diagnosis of bone metastasis of HCC secondary to HBV infection was accepted. Conclusion: Bone metastases from HCC should be considered when a patient with chronic liver disease presents with bone pain.


Journals System - logo
Scroll to top