The role of the MIND diet in prevention and treatment of Alzheimer's disease: A Literature Review
 
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1
Student of the Faculty of Medicine, Medical University of Warsaw, Poland
 
2
Student of the Faculty of Medicine, Poznan University of Medical Sciences, Poland
 
 
Submission date: 2025-11-10
 
 
Final revision date: 2026-01-12
 
 
Acceptance date: 2026-01-23
 
 
Publication date: 2026-02-27
 
 
Corresponding author
Jan Krupa   

Student of the Faculty of Medicine, Medical University of Warsaw, Poland
 
 
Wiadomości Lekarskie 2026;(2):390-398
 
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ABSTRACT
Introduction and Objective: Alzheimer’s disease (AD) remains a leading cause of cognitive decline worldwide, with no effective pharmacological treatment currently available. Recent research increasingly point to modifiable risk factors, especially dietary patterns, as potential tools to prevent or delay neurodegeneration. This review evaluates the impact of the MIND diet on the prevention and progression of AD and compares it with other dietary interventions. Materials and methods: A literature search was conducted using the PubMed and Google Scholar databases for articles published from January 2015 to January 2025, focusing on the influence of the MIND diet, as well as other dietary patterns, on AD progression and cognitive performance. Results: A high intake of foods rich in substances with anti-inflammatory and antioxidant properties appear to have neuroprotective properties by reducing oxidative stress and improving vascular health. Cohort studies and observational analyses consistently suggest that adherence to the MIND diet is associated with slower cognitive decline and a reduced risk of AD. Conclusions: While the MIND diet shows promise as a feasible non-pharmacological strategy, current evidence is largely observational and limited by population heterogeneity and inconsistent adherence definitions. Short-term randomized controlled trials are less conclusive. Long-term clinical trials are needed to establish causality. Despite these limitations, the MIND diet remains a practical and potentially effective approach to reducing cognitive decline and delaying the onset of AD.
eISSN:2719-342X
ISSN:0043-5147
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