Non-invasive assessment of liver steatosis in children: The role of steatometry and metabolic markers
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1
Medicine faculty, Uzhhorod National University, Ukraine
2
Hepatology, Institute of Elastography, Ukraine
Publication date: 2026-05-29
Corresponding author
Olha Pushkarenko
Medicine faculty, Uzhhorod National University, Narodna, 88000, Uzhhorod, Ukraine
Wiadomości Lekarskie 2026;(5):945-951
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ABSTRACT
Aim:
The aim of this study was to assess the prevalence and staging of steatotic liver disease among overweight adolescents using non-invasive diagnostic methods, as well as to analyse metabolic correlations and the effectiveness of lifestyle interventions.
Material and methods:
The study included 42 overweight children aged 12-18. Disease was diagnosed using ultrasound steatometry, shear wave elastography and biochemical indicators. Correlation analysis was performed. A six-month lifestyle modification programme was implemented, including dietary modification, physical activity and psychological support. Changes in the degree of steatosis, metabolic parameters were monitored before and after.
Results:
Metabolic dysfunction–associated steatotic liver disease was detected in 88% of participants, of which 52.4% were in stage S1, 35.7% in stage S2, and 11.9% in stage S3. No fibrosis was detected in any patient. Stage S1 steatosis was asymptomatic, while stages S2 and S3 were associated with metabolic disorders, insulin resistance and micronutrient deficiencies. After the intervention, there was a significant reduction in hepatic fat accumulation, with the attenuation coefficient decreasing by 40%. Patients with stage S3 showed improvement in triglyceride levels, insulin sensitivity, and normalisation of liver enzymes.
Conclusions:
Steatometry is an effective non-invasive method for diagnosing early-stage metabolic dysfunction–associated steatotic liver disease. Lifestyle interventions, including dietary correction, physical activity, and psychological support, significantly improve liver condition and metabolic parameters in adolescents. Early detection and treatment are crucial for preventing disease progression and related metabolic complications in adulthood.